Snowman, known as Jimmy before mankind was overwhekned by a plague, is truggling to survive in a world where he may be the last human, and mourning the loss of his best friend, Crake, and the beautiful and elusive Oryx whom they both loved. In search of answers, Snowman embarks on a journey-with the help of the green-eyed Children of Crke-through the lush wilderness that was so recently a great city; until powerful corporations took mankind on an uncontrolled genetic engineering ride.